2-Aminobenzaldehyde
Description Physical properties Uses Preparation Reference- Product Name
- 2-Aminobenzaldehyde
- CAS No.
- 529-23-7
- Chemical Name
- 2-Aminobenzaldehyde
- Synonyms
- ANTHRANILALDEHYDE;O-AMINOBENZALDEHYDE;2-amino-benzaldehyd;Benzaldehyde, 2-amino-;2-Formylaniline;Ambroxol Imp.14;2-Aminobenzaldeyhde;2-AMINOBENZALDEHYDE;Benzaldehyde,2-amino-;Bromhexine Impurity 11
- CBNumber
- CB7279021
- Molecular Formula
- C7H7NO
- Formula Weight
- 121.14
- MOL File
- 529-23-7.mol
2-Aminobenzaldehyde Property
- Melting point:
- 38°C
- Boiling point:
- 225.84°C (rough estimate)
- Density
- 1.1344 (rough estimate)
- refractive index
- 1.5323 (estimate)
- Flash point:
- 113 °C
- storage temp.
- -20°C
- pka
- -0.01±0.10(Predicted)
- form
- Low Melting Solid
- color
- White to yellow
- Stability:
- Unstable: reported to polymerize rapidly at room temperature. Incompatible with strong oxidizing agents, strong bases. Store at -20 C.
- LogP
- 1.080 (est)
- CAS DataBase Reference
- 529-23-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Aminobenzaldehyde(529-23-7)
- EPA Substance Registry System
- Benzaldehyde, 2-amino- (529-23-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- WGK Germany
- 3
- F
- 8-10-23
- HS Code
- 29223990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A9628
- Product name
- 2-Aminobenzaldehyde
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $108
- Updated
- 2024/03/01
- Product number
- A9628
- Product name
- 2-Aminobenzaldehyde
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $257
- Updated
- 2024/03/01
- Product number
- A9628
- Product name
- 2-Aminobenzaldehyde
- Purity
- ≥98%
- Packaging
- 500mg
- Price
- $160
- Updated
- 2024/03/01
- Product number
- J55628
- Product name
- 2-Aminobenzaldehyde
- Packaging
- 1g
- Price
- $26
- Updated
- 2021/12/16
- Product number
- 4630-1-26
- Product name
- 2-Aminobenzaldehyde
- Packaging
- 500mg
- Price
- $56
- Updated
- 2021/12/16
2-Aminobenzaldehyde Chemical Properties,Usage,Production
Description
2-Aminobenzaldehyde is one of the three isomers of aminobenzaldehyde. It is used as a versatile substrate for rhodium-catalyzed alkyne hydroacylation.1 It is used to prepare quinoline derivatives as antiviral agents, electroluminescent materials for OLEDs, and 2-tosylaminopheyl cyclopropylmethanols for gold-catalyzed cyclopropyl carbinol rearrangement. It is also used for the Friedländer-type synthesis, the benzyl C-H bond amination of acrymethylamines catalyzed by hydroxy-TEMPO, and for silver-catalyzed aniline mediated cascade hydroamination/cycloaddition reactions.
Physical properties
2-Aminobenzaldehyde has recently been identifed as an important component in the fragrant scents of many flowers. These flowers include broom (Spartium junceum), false acacia (Robinia pseudoacacia), European bird cherry (Padus avium), ily (Lilium candidum), seringat (Philadelphus coronarius), Pittosporum tobira, Hypecoum imberbe, and H. fragrant. This chemical is also responsible for the“"sweet" or fragrant odor of the wild mushroom Hebeloma sacchariolens.
Uses
Reactant for:
Preparation of quinoline derivatives as antiviral agents
Preparation of electroluminescent materials for OLEDs
Friedlander-type synthesis
Preparation of 2-tosylaminophenyl cyclopropylmethanols for gold-catalyzed cyclopropyl carbinol rearrangement
Benzyl C-H bond amination of arylmethylamines catalyzed by hydroxy-TEMPO
Silver-catalyzed aniline mediated cascade hydroamination/cycloaddition reactions
Preparation
2-Aminobenzaldehyde is prepared by reduction of 2- nitrobenzaldehyde with aqueous ferrous sulfate and ammonia. Since the product contains both aldehyde and amino groups it polymerizes easily. This means that it must be isolated rapidly after it forms, which is done by steam distillation of the product from the reaction mixture.
Reference
M. Castaing, S. L. Wason, B. Estepa, J. F. Hooper, M. C. Willis, 2‐Aminobenzaldehydes as Versatile Substrates for Rhodium‐Catalyzed Alkyne Hydroacylation: Application to Dihydroquinolone Synthesis, Angewandte Chemie, 2013, vol. 52, pp. 13280-13283
Chemical Properties
light yellow crystalline powder
Uses
Reactant for:
- Preparation of quinoline derivatives as antiviral agents
- Preparation of electroluminescent materials for OLEDs
- Friedlander-type synthesis
- Preparation of 2-tosylaminophenyl cyclopropylmethanols for gold-catalyzed cyclopropyl carbinol rearrangement
- Benzyl C-H bond amination of arylmethylamines catalyzed by hydroxy-TEMPO
- Silver-catalyzed aniline mediated cascade hydroamination/cycloaddition reactions
Purification Methods
Distil it in steam and recrystallise it from H2O or EtOH/ Et2O. The semicarbazone has m 247o. [Beilstein 14 H 21, 14 I 356, 14 II 14, 14 III 47, 14 IV 42.]
2-Aminobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Aminobenzaldehyde manufacturers
- Product
- 2-Aminobenzaldehyde 529-23-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 2-Aminobenzaldehyde 529-23-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-10-20
- Product
- 2-Aminobenzaldehyde 529-23-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-12-23